Buscar
Mostrando ítems 1-10 de 1395
Updates on the production of therapeutic antibodies using human hybridoma technique
(Bentham Science Publishers, 2016)
Novel hybrid lipid nanocapsules loaded with a therapeutic monoclonal antibody – Bevacizumab – and Triamcinolone acetonide for combined therapy in neovascular ocular pathologies
(Elsevier Science, 2021-02)
The aim of this study was to design and develop a novel hybrid formulation based on lipid nanocapsules containing bevacizumab (BVZ), an effective therapeutic antibody, on the surface and triamcinolone acetonide (TA) in the ...
Chemokine receptor-specific antibodies in cancer immunotherapy: Achievements and challenges
(Frontiers Research Foundation, 2015-01)
The 1990s brought a burst of information regarding the structure, expression pattern, and role in leukocyte migration and adhesion of chemokines and their receptors. At that time, the FDA approved the first therapeutic ...
Therapeutic monoclonal antibodies: scFv patents as a marker of a new class of potential biopharmaceuticals
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2011)
Monoclonal antibodies represent the fastest growing class of biopharmaceutical products and have a host of applications in medical research, diagnosis, therapy, and basic science. The production of recombinant monoclonal ...
Patentability of monoclonal antibodies in Brazil: analysis of non-obviousness requirement
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Membrane binding, endocytic trafficking and intracellular fate of high-affinity antibodies to gangliosides GD1a and GM1
(Elsevier Science, 2017-01)
Gangliosides are glycolipids embedded in the outer leaflets of the plasma membrane. Antibodies against GM1 and GD1a gangliosides are associated with selective dysfunction of motor axons in peripheral neuropathies, and ...
Characterization and production of IgY antibodies anti-Photobacterium damselae subsp. piscicida: Therapeutic and prophylactic use in Rachycentron canadum
(2019-11-15)
Pseudotuberculosis is caused by Photobacterium damselae subsp. piscicida (Phdp), an important pathogen in marine fish culture. In this study, Phdp isolated from a Rachycentron canadum farm was used to produce anti-Photobacterium ...
Heterologous hyperimmune polyclonal antibodies against SARS-COV-2: A broad coverage, affordable, and scalable potential immunotherapy for Covid-19
(2021-09)
The emergence and dissemination of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the resulting COVID-19 pandemic triggered a global public health crisis.
Although several SARS-CoV-2 vaccines have ...
High anti-Leishmania IgG antibody levels are associated with severity of mucosal Leishmaniasis
(Frontiers Media, 2021)