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Gating of two-pore domain K+ channels by extracellular pH
(Portland Press on behalf of The Biochemical Society, 2008)
Structure-based study of TASK channels blockers
(2016)
Two-pore domain potassium (K2P) channels trigger the background K+
currents in mammalian cells. K2P channels are separated into six subfamilies
based on their structural and functional properties. The acid-sensitive ...
Side Fenestrations Provide an "anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels
(American Chemical Society, 2017)
Rational drug design targeting two-pore domian potassium channels TASK. Theoretical - Experimental approximation
(2014)
TASK-‐3
is
a
two-‐pore
domain
potassium
(K2P)
channel
highly
expressed
in
hippocampus,
cerebellum,
and
cortex.
TASK-‐3
regulates
neurotransmitter
functions
and
has
been
identified
as
an
oncogenic
potassium
channel
and ...
Study and discovery of TASK potassium channels modulators: A theoretical and experimental approach
(2016)
TASK-‐3
is
a
two-‐pore
domain
potassium
(K2P)
channel
highly
expressed
in
hippocampus,
cerebellum,
and
cortex.
TASK-‐3
regulates
neurotransmitter
functions
and
has
been
identified
as
an
oncogenic
potassium
channel
and ...
Intracellular Blockers Design Targeting TASK-3 Potassium Channels
(2015)
TASK-‐3
is
a
two-‐pore
domain
potassium
(K2P)
channel
highly
expressed
in
hippocampus,
cerebellum
and
cortex.
TASK-‐3
regulates
neurotransmitter
functions
as
well
as
the
mediating
effect
of
the
neurotransmitter
activa ...
Rational design and synthesis of selective blockers of the K2P channel TASK-3.
(2015)
K+ channels allow the selective transfer of K+ ions inside or outside of the cell. Within this
family we find K2P channels, with four transmembrane segments and two pore domains
per subunit to form a functional dimer. These ...