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The synthesis of C-2 symmetry diesters of (3R,4R)-TTFOL through a green and stereoselective (2R,3R)-TADDOL rearrangement
(Elsevier, 2015)
An efficient, green, and atom economic methodology for the stereoselective synthesis of C-2 symmetry (3R,4R)-TTFOL diester derivatives has been developed. The procedure occurs through a (2R,3R)-TADDOL dioxolane cleavage ...
Toward the cholinesterase inhibition potential of TADDOL derivatives: Seminal biological and computational studies
(2022)
Alzheimer's disease (AD) is a degenerative neurological disease characterized by gradual loss of cognitive skills and memory. The exact pathogenesis involved still remains unrevealed, but several studies indicate the ...
Diseño, síntesis y evaluación de novedosos ligandos quirales derivados de TADDOL
(2012-08-03)
La preparación enantioselectiva de moléculas quirales se conoce como síntesis asimétrica. Las moléculas que no pueden superponerse se llaman enantiómeros y deben ser considerados como compuestos químicos diferentes, en ...
Efficient asymmetric TADDOLs-organocatalyzed cycloaddition for the synthesis of allyltin derivatives
(Elsevier Science, 2014-09)
We report here the results obtained in the study of organocatalytic asymmetric Diels–Alder reactions to optimize the synthesis of stereo defined allyltin derivatives using (Z)-2-(1-cyclohexenyl)-1-ethenyl(trineophyl)stannane ...
Stereoselective synthesis and some properties of new chlorodiorganotin- substituted macrodiolides
(American Chemical Society, 2012-01)
Radical tandem addition of dialkyltin chlorohydrides, R2SnHCl (R = n-Bu, neophyl, Ph), to TADDOL's substituted diacrylates (47) led to the corresponding products of cyclohydrostannation. The new optically active ...
Synthesis of organotin derivatives of optically active eleven-membered macrodiolides
(Pergamon-Elsevier Science Ltd, 2016-05-01)
The synthesis and the results obtained in the hydrostannation of eight new TADDOL diacrylates and methacrylates are reported. The addition of triorganotin hydrides, R3SnH, 12-14 (R = nBu, neophyl, Ph, respectively) to ...
Synthesis of unsaturated diesters of primary, secondary and tertiary diols derived from dimethyl (+)-tartrate and galactaric acid
(Wiley VCH Verlag, 2013-07)
The preparation of symmetrical unsaturated diesters of dioe first was the reaction of mixed anhydrides, obtained from α,β-unsaturated acids and benzoyl chloride, with diols 3 (primary), 5 (secondary), and 7 (primary), i.e., ...