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Editorial: Epitope discovery and Synthetic Vaccine design
(Frontiers Media Sa, 2018)
Complex network study of the immune epitope database for parasitic organisms
(Bentham Science Publishers B.V., 2017)
A study of the Immune Epitope Database for some fungi species using network topological indices
(Springer International Publishing, 2017)
T Cell Epitope Predictions
(Annual Reviews, 2020-04)
Throughout the body, T cells monitor MHC-bound ligands expressed on the surface of essentially all cell types. MHC ligands that trigger a T cell immune response are referred to as T cell epitopes. Identifying such epitopes ...
In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine
(Elsevier, 2018-04)
Background: Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane ...
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic involving so far more than 15 million infections and 630,211 deaths. Effective vaccines are urgently needed to prevent SARS-CoV-2 infections. ...
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic
involving so far more than 15 million infections and 630,211 deaths. Effective vaccines are
urgently needed to prevent SARS-CoV-2 infections. ...
Automatic Generation of Validated Specific Epitope Sets
(Hindawi, 2015)
Accurate measurement of B and T cell responses is a valuable tool to study autoimmunity, allergies, immunity to pathogens, and host-pathogen interactions and assist in the design and evaluation of T cell vaccines and ...
The Immune Epitope Database and Analysis Resource Program 2003–2018: reflections and outlook
(Springer, 2019-11)
The Immune Epitope Database and Analysis Resource (IEDB) contains information related to antibodies and T cells across an expansive scope of research fields (infectious diseases, allergy, autoimmunity, and transplantation). ...
Antibody specific B-cell epitope predictions: Leveraging information from antibody-antigen protein complexes
(Frontiers Media S.A., 2019-02)
B-cells can neutralize pathogenic molecules by targeting them with extreme specificity using receptors secreted or expressed on their surface (antibodies). This is achieved via molecular interactions between the paratope ...