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Assessment of the stereoselective fungal biotransformation of albendazole and its analysis by HPLC in polar organic mode
(ELSEVIER SCIENCE BVAMSTERDAM, 2013-08-02)
A high-performance liquid chromatographic method using polar organic mode was developed to analyze albendazole (ABZ), albendazole sulfone (ABZSO(2)) and the chiral and active metabolite albendazole sulfoxide (ABZSOX, ...
Solid phase microextraction and LC-MS/MS for the determination of paliperidone after stereoselective fungal biotransformation of risperidone
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The present work describes for the first time the use of SPME coupled to LC-MS/MS employing the polar organic mode in a stereoselective fungal biotransformation study to investigate the fungi ability to biotransform the ...
X-ray crystal structures of intermediates of the stereoselective (±)-grandisol synthesis based on the remote alkylation protocol
(SpringerNew York, 2013-05)
Starting from easily prepared (cyclobutylsulfonyl) benzene (1), a stereoselective synthesis of (±)-grandisol, accomplished in nine steps, with an overall yield of ca. 18 %, has been presented by Monteiro and Stefani (Eur ...
Inhibition of IL-2 production by novel small molecules using building blocks from reduced chalcones and a substituted proline
(Bentham Science Publishers B.V., 2018)
Stereoselective analysis of carvedilol in human plasma and urine using HPLC after chiral derivatization
(John Wiley & Sons Ltd, 2008-07-01)
An enantioselective high-performance liquid chromatographic method for the analysis of carvedilol in plasma and urine was developed and validated using (-)-menthyl chloroformate (MCF) as a derivatizing reagent. Chloroform ...
Multicomponent approach to silica-grafted peptide catalysts : A 3 D continuous-flow organocatalytic system with on-line monitoring of conversion and stereo-selectivity
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2014-11-28)
The derivatization of organocatalysts with functional appendages suitable to anchor onto solid supports is usually achieved by stepwise syntheses. As an alternative to such a strategy, this work describes a one-pot approach ...
An easy and efficient method to produce gamma-amino alcohols by reduction of beta-enamino ketones
(Sociedade Brasileira de Química, 2004)
Development of an enantioselective capillary electrophoretic method for the simultaneous determination of montelukast enantiomeric and diastereoisomeric forms and its main degradation product
(Wiley VCH Verlag, 2016-06)
A stereoselective CD-MEKC system has been developed for the quality control of Montelukast(MK), commercialized as a pure enantiomer. The proposedmethod is the first onethat allows the simultaneous determination ofMK, its ...
Stereoselective analysis of thioridazine-2-sulfoxide and thioridazine-5-sulfoxide: An investigation of rac-thioridazine biotransformation by some endophytic fungi
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The purpose of this study was to develop a method for the stereoselective analysis of thioridazine-2-sulfoxide (THD-2-SO) and thioridazine-5-sulfoxide (THD-5-SO) in culture medium and to study the biotransformation of ...