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Language Deficits as a Preclinical Window into Parkinson's Disease: Evidence from Asymptomatic Parkin and Dardarin Mutation Carriers
(Cambridge University Press, 2017-02)
Objectives: The worldwide spread of Parkinson's disease (PD) calls for sensitive and specific measures enabling its early (or, ideally, preclinical) detection. Here, we use language measures revealing deficits in PD to ...
LRRK-2 as a Key Molecule Bridging Inflammation to Parkinson's Disease
(IOS Press, 2013-11)
The pathogenetic mechanisms leading to typical Parkinson's Disease (PD), the second most common human neurodegenerative disorder remains unknown. Genetic variants of Leucine-Rich Repeat Kinase 2 (LRRK-2) are associated ...
Síntomas no motores en pacientes con enfermedad de Parkinson Hospital de San José, Bogotá, DC Colombia
(Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud, 2012-03-01)
Propagation Of Pathology Through Brain Networks In Neurodegenerative Diseases: From Molecules To Clinical Phenotypes
(WILEY-BLACKWELLHOBOKEN, 2015)
ER stress and Parkinson's disease: Pathological inputs that converge into the secretory pathway
(Elsevier, 2016)
The major clinical feature of Parkinson's disease (PD) is impairment in motor control as a result of extensive dopaminergic neuron loss in the substantia nigra pars compacta. The central pathological hallmark of PD is the ...