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Receptors coupling to G proteins: Is there a signal behind the sequence?
(Wiley-Blackwell, 2000-12-01)
Upon the binding of their ligands, G protein-coupled receptors couple to the heterotrimeric G proteins to transduce a signal. One receptor family may couple to a single G protein subtype and another family to several ones. ...
In silico characterization of putative members of the coffee (Coffea arabica) ethylene signaling pathway
(Fundação de Pesquisas Científicas de Ribeirão Preto, 2017)
A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
(Elsevier B.V., 2004-08-06)
Literature studies, 3D structure data, and a series of sequence analysis techniques were combined to reveal important residues in the structure and function of the ligand-binding domain of nuclear hormone receptors. A ...
Structural biology of chemokine receptors
(Sociedad de Biología de Chile, 1999)
Novel antibodies directed against the human erythropoietin receptor: Creating a basis for clinical implementation
(Wiley, 2014)
Recombinant human erythropoietin (rHuEPO) is an effective treatment for anaemia but concerns that it causes disease progression in cancer patients by activation of EPO receptors (EPOR) in tumour tissue have been controversial ...
Allosteric Pathways In The Ppar Gamma-rxr Alpha Nuclear Receptor Complex
(NATURE PUBLISHING GROUPLONDON, 2016)