In protein evolution, due to functional and biophysical constraints, the rates of amino acid substitution differ from site to site. Among the best predictors of site-specific rates are solvent accessibility and packing ...

The backbone potential energy surface (PES) (Ramachandran map) of N-acetyl-L-glutamine-N-methylamide has been studied at a,a side-chain orientation. Side-chain PESs at selected backbone conformations (γL and βL) were also ...

A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole ...

A selective route for the degradation of the unsaturated side chain of ent-labdanes has been devised, giving two useful synthons: 2β-acetoxy-14, 15,17-trinor-ent-labdane-8,13-dione (5) and 2β-acetoxy-14,15-dinor-ent- ...

A route for the degradation of the side chain of ent-labdane derivatives has been devised, giving the useful synthon 2β,12-dihydroxy-13,14,15,16,17- pentanor-ent-labdane-8-one (8). The use of this compound in the preparation ...

This paper proposes a novel simulator of energy consumption patterns that allows designing demand side management(DSM) strategies without economic incentives. The simulator emulates consumers’patterns with and without ...

We report on the results of X-ray investigations in two series of polymer monomer composites, PM6Rm-33 and PMnR12-33, which consist of mixtures of achiral liquid crystalline side chain polymers and their monomers. These ...

Thermogravimetric analyses of fractions of poly(2-chloroethyl methacrylate) (P2CEM), poly(3-chloropropyl methacrylate) (P3CPM), poly(di-2-chloroethyl itaconate) (PD2CEI) and poly(di-3-chloropropyl itaconate) (PD3CPI) of ...

The dependence of the 13C chemical shift on side-chain orientation was investigated at the density functional level for a two-strand antiparallel β-sheet model peptide represented by the amino acid sequence Ac-(Ala)3-X-(Ala)12- ...