Artículos de revistas
Side-chain Modifications of Highly Functionalized 3(2H)-Furanones
Fecha
2012Registro en:
MOLECULES, BASEL, v. 17, n. 10, supl. 1, Part 1, pp. 12151-12162, OCT, 2012
1420-3049
10.3390/molecules171012151
Autor
Nardini, Viviani
Rodrigues, Shirley Muniz Machado
Constantino, Mauricio Gomes
Silva, Gil Valdo Jose da
Institución
Resumen
A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reaction between 3-butyn-2-ol and nitrile oxide.