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Estudo de associação de SNPs com a predisposição ao desenvolvimento de câncer de tireoide em pacientes da Liga Norte-Riograndense Contra o Câncer
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FARMACÊUTICAS, 2018-03-09)
Thyroid cancer (CT) is the most common endocrine tumor and accounts for 1% of all malignancies. The number of cases diagnosed has been increasing and it is estimated that 212 thousand new cases will appear each year in the ...
Development of a small panel of SNPs to infer ancestry in chileans that distinguishes Aymara and Mapuche components
(Sociedad de Biología de Chile, 2020)
Background Current South American populations trace their origins mainly to three continental ancestries, i.e. European, Amerindian and African. Individual variation in relative proportions of each of these ancestries may ...
Identificação de SNPs em sequências de microRNAs de suínos e os possíveis efeitos na predição de transcritos alvo
(Universidade Estadual Paulista (Unesp), 2019-05-27)
Os microRNAs (miRNAs) são pequenos RNAs não-codificadores (20-22 nucleotídeos) que exercem uma função de controle pós-transcricional em RNA mensageiro (RNAm), regulando a produção de proteínas. Variações genéticas, como ...
Evaluation of imputation accuracy using the combination of two high-density panels in Nelore beef cattle
(Nature Publishing Group, 2019-11-29)
This study compared imputation from lower-density commercial and customized panels to high-density panels and a combined panel (Illumina and Affymetrix) in Nelore beef cattle. Additionally, linkage disequilibrium and ...
Detecção de QTL para maciez da carne em bovinos da raça Nelore
(Universidade Estadual Paulista (Unesp), 2016-07-29)
O mercado consumidor tem sido cada vez mais exigente quanto à qualidade da carne e, portanto, a pecuária precisa melhorar sua eficiência e fornecer produtos diferenciados, padronizados e com qualidade. Entre as características ...
Assessing the accuracy of imputation in the gyr breed using different SNP panels
(2021-01-01)
The aim of this study was to evaluate the accuracy of imputation in a Gyr population using two medium- density panels (Bos taurus - Bos indicus) and to test whether the inclusion of the Nellore breed increases the imputation ...
Association between single nucleotide polymorphisms and sexual precocity in Nellore heifers
(2017-02-01)
The aim of this study was to determine the extent (r2) of linkage disequilibrium (LD) in the genome of Nellore cattle, and to examine associations between single nucleotide polymorphisms (SNP) and age at first calving (AFC) ...
Applicability of the SNPforID 52-plex panel for human identification and ancestry evaluation in a Brazilian population sample by next-generation sequencing
(2019-05-01)
SNP analysis is of paramount importance in forensic genetics. The development of new technologies in next-generation sequencing allowed processing a large number of markers in various samples simultaneously. Although SNPs ...