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New small-size peptides possessing antifungal activity
(Elsevier, 2010-01)
The synthesis, in vitro evaluation, and conformational study of a new series of small-size peptides acting as antifungal agents are reported. In a first step of our study we performed a conformational analysis using Molecular ...
Targeting tumors using peptides
(Multidisciplinary Digital Publishing Institute, 2020-02)
To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure ...
Study cases of enzymatic processes
(Springer, 2008)
Peptides are heteropolymers composed by amino acid residues linked by peptidic bonds between the carboxyl group of one amino acid residue and the α-amino group of the next one. The definition is rather vague in terms of ...
Amyloid formation by short peptides in the presence of dipalmitoylphosphatidylcholine membranes
(American Chemical Society, 2020-11-19)
The aggregation of two short peptides [RF] and [RF]4 (where R = arginine and F = phenylalanine) with dipalmitoylphosphatidylcholine (DPPC) model membranes was investigated at the air-water interface using the Langmuir ...
New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design
(Taylor & Francis, 2016-03)
We report here two new small-size peptides acting as modulators of the β-site APP cleaving enzyme 1 (BACE1) exosite. Ac-YPYFDPL-NH2 and Ac-YPYDIPL-NH2 displayed a moderate but significant inhibitory effect on BACE1. These ...
Saddle-curvature instability of lipid bilayer induced by amphipathic peptides: a molecular model
(2020-06-07)
Amphipathic peptides that partition into lipid bilayers affect the curvature elastic properties of their host. Some of these peptides are able to shift the Gaussian modulus to positive values, thus triggering an instability ...
Immunomodulating effects of peptidic fractions issued from milk fermented with Lactobacillus helveticus
(American Dairy Science Association, 2002-11)
The effect of peptides released during the fermentation of milk on the humoral immune system and on fibrosarcoma growth was studied. Lactobacillus helveticus was able to release peptidic compounds during milk fermentation ...
Penetratin and derivatives acting as antibacterial agents
(Wiley, 2013-06)
The synthesis, in vitro evaluation and conformational study of penetratin and structurally related derivatives acting as antibacterial agents are reported. Among the compounds evaluated here, two methionine sulphoxide ...
Gill tissues of the mussel Mytilus edulis chilensis: A new source for antimicrobial peptides
(Pontificia Universidad Católica de Valparaíso, 2005)
SacRALF1, a peptide signal from the grass sugarcane (Saccharum spp.), is potentially involved in the regulation of tissue expansion
(SPRINGER, 2010)
Rapid alkalinization factor (RALF) is part of a growing family of small peptides with hormone characteristics in plants. Initially isolated from leaves of tobacco plants, RALF peptides can be found throughout the plant ...