The specific role of the chloride anion (Cl−) as a signalling effector or second messenger has been increasingly recognized in recent years. It could represent a key factor in the regulation of cellular homeostasis. Changes ...

In biochemical signaling pathways without explicit feedback connections, the core signal transduction is usually described as a one-way communication, going from upstream to downstream in a feedforward chain or network of ...

Compressive sensing is a new field in signal processing and applied mathematics. It allows one to simultaneously sample and compress signals which are known to have a sparse representation in a known basis or dictionary ...

How signaling gradients supply positional information in a field of moving cells is an unsolved question in patterning and morphogenesis. Here, we ask how a Wnt signaling gradient regulates the dynamics of a wavefront of ...

Immune cells are modulated through the crosslinking of receptors named “immunoreceptors”. Ligation of immunoreceptors by their ligands induces a tyrosine-phosphorylation signal that is essential for cell activation or ...

Previous studies have demonstrated that double phosphorylation of a protein can lead to bistability if some conditions are fulfilled. It was also shown that the signaling behavior of a covalent modification cycle can be ...

Unraveling the molecular processes involved in the genesis, differentiation, and cell death of the nervous system is an intense and continual interest of the neuroscience community. In recent years, the preponderance of ...

Living cells have developed a set of complex signaling responses, which allow them to withstand different environmental challenges. Signaling pathways enable the cell to monitor external and internal states and to articulate ...

Voice signal classification in three types according to their degree of periodicity, a task known as signal typing, is a relevant preprocessing step before computing any perturbation measures. However, it is a time consuming ...

Hydrogen sulphide (H2S) is an endogenously produced gasotransmitter that has rapidly emerged as an active signalling component of several plant processes, stomatal movement regulation among them. The guard cells (GCs), ...