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Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation
(1992)
In this work the microsomal lauric acid ω-hydroxylation, fatty acid peroxisomal β-oxidation, and the levels of cytochrome P-450 IVAI were studied in liver tissue from starved rats. Starvation increased the peroxisomal ...
Starvation effect on rat kidney peroxisomal and microsomal fatty acid oxidation. A comparative study between liver and kidney
(1993)
Microsomal lauric acid 12-hydroxy lauric acid (ω)-hydroxylation and fatty acid peroxisomal β-oxidation were studied in kidney tissue from starved rats. Starvation increased the microsomal ω-hydroxylation and peroxisomal ...
Mechanisms underlying the inhibition of the cytochrome P450 system by copper ions
(WILEY, 2009)
Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In ...
In Vitro Metabolism of Artepillin C by Rat and Human Liver Microsomes
(2017-05-01)
Artepillin C, a natural product present in the Brazilian green propolis, has several biological properties. Among these properties, the antitumor action of this product is noteworthy and makes it a promising drug candidate ...
Identification of biotransformation products of disperse dyes with rat liver microsomes by LC-MS/MS and theoretical studies with DNA: Structure-mutagenicity relationship using Salmonella/microsome assay
(2018-02-01)
Azo dyes are known as a group of substances with DNA damage potential that depend on the nature and number of azo groups connected to aromatic rings (benzene and naphthalene), chemical properties, e.g. solubility and ...
In vitro metabolism of copalic and kaurenoic acids in rat and human liver microsomes
(2021-01-01)
Copalic (CA) and kaurenoic (KA) acids are the main diterpenes found in the oleoresin extracted from the copaiba tree (Copaifera sp). This study aimed to characterize the metabolism of CA and KA in rat and human liver ...
Modulation of rat liver cytochrome P450 activity by prolonged red wine consumption
(2002)
Cytochrome P450-dependent oxidation of lauric acid, p-nitrophenol and ethanol by liver microsomal fractions were studied in control rats and in animals given either ethanol, red wine, or alcohol-free red wine for 10 weeks. ...