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Bases moleculares e efeitos de retinóides em células tumorais
(2004)
Os retinóides são um grupo de substâncias reguladoras do crescimento que incluem o ácido trans-retinóico (tRA), um
derivado metabólico natural da vitamina A (retinol), o seu isômero 9-cis (cAR) e uma série de derivados ...
Impact of VDR and RXR expression in non-melanoma skin cancer pathogenesis
(2022-01-01)
1,25(OH)2D3, the active form of vitamin D, has been extensively studied for its putative protective activities against tumors. It does biological work by connecting to a nuclear receptor called VDR, which heterodimerizes ...
Bases moleculares e efeitos de retinóides em células tumorais
(Instituto de Ciências da Saúde/ Universidade Federal da BahiaBrasil, 2004)
Os retinóides são um grupo de substâncias reguladoras do crescimento que incluem o ácido trans-retinóico (tRA), um
derivado metabólico natural da vitamina A (retinol), o seu isômero 9-cis (cAR) e uma série de derivados ...
Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface
(2007-08-01)
The orphan receptor nerve growth factor-induced B (NGFI-B) is a member of the nuclear receptor's subfamily 4A (Nr4a). NGFI-B was shown to be capable of binding both as a monomer to an extended half-site containing a single ...
Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface
(2007-08-01)
The orphan receptor nerve growth factor-induced B (NGFI-B) is a member of the nuclear receptor's subfamily 4A (Nr4a). NGFI-B was shown to be capable of binding both as a monomer to an extended half-site containing a single ...
Daily oscillation of glutathione redox cycle is dampened in the nutritional vitamin A deficiency
(Taylor & Francis Ltd, 2012-08)
Examples of hormonal phase-shifting of circadian gene expression began to emerge a few years ago. Vitamin A fulfills a hormonal function by binding of retinoic acid to its nuclear receptors, RARs and RXRs. We found retinoid- ...
Low resolution structures of the retinoid X receptor DNA-binding and ligand-binding domains revealed by synchrotron x-ray solution scattering
(The American Society for Biochemistry and Molecular Biology, 2013)