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Molecular Design, Synthesis and Evaluation of 2,3-Diarylquinoxalines as Estrogen Receptor Ligands
(Bentham Science Publ Ltd, 2015-01-01)
Selective Estrogen Receptor Modulators (SERMs) are characteristically capable of being antagonist and agonist of estrogen receptors and, therefore, they can inhibit or stimulate estrogen production in different tissues. ...
Estrogen receptor: Structural differences and potential implications on selectivity examined by the GRID/CPCA approach
(BENTHAM SCIENCE PUBL LTD, 2008)
Selective Estrogen Receptor Modulators ( SERMs) have been developed, but the selectivity towards the subtypes ( ER or ER is not well understood. Based on three-dimensional structural properties of ligand binding domains, ...
Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
(2019-01)
Synthetic selective modulators of the estrogen receptors (SERMs) have shown to protect neurons and glial cells against toxic insults. Among the most relevant beneficial effects attributed to these compounds are the regulation ...
Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
(Facultad de Ciencias de la Salud, 2019)
Synthetic selective modulators of the estrogen receptors (SERMs) have shown to protect neurons and glial cells against toxic insults. Among the most relevant beneficial effects attributed to these compounds are the regulation ...
Procoagulant state after raloxifene therapy in postmenopausal women
(2005)
Objective: To investigate the effects of raloxifene on the hemostatic system in postmenopausal women.
Design: A prospective longitudinal study.
Setting: Outpatient clinic of the Faculty of Medicine of Ribeirão Preto, ...
Astrocytes Mediate Protective Actions of Estrogenic Compounds after Traumatic Brain Injury
(Facultad de Ciencias de la Salud, 2019)
Traumatic brain injury (TBI) is a serious public health problem. It may result in severe neurological disabilities and in a variety of cellular metabolic alterations for which available therapeutic strategies are limited. ...
Molecular mechanisms involved in the protective actions of Selective Estrogen Receptor Modulators in brain cells
(Academic Press Inc., 2019)