A convenient synthetic approach to a cyclodeca[ij]isoquinoline derivative, which embodies the carbon skeleton of excentricine and related stephaoxocanes, is described. The synthesis involves the combined use of ring closing ...

In this work, some aspects of the chemistry of N-heterocyclic carbenes (NHC) are investigated. Charpter 1 presents a brief literature review comprising the historical aspects, the synthesis, the organometallic chemistry, ...

In this work, a study of different synthetic ways was made in order to obtain spiro compounds starting from R-(-)-carvone, getting to the formation of cycloheptenone as an intermediate, which undergoes two consecutives ...

While heterocycles are a key feature frequently found in compounds with pharmaceutical or agrochemical interest, the combination between solidsupported synthesis and organometallic chemistry has demonstrated to be a helpful ...

Deuterium-labeled compounds have been of great interest in recent years due to their diverse applications. For instance, they can be used in mechanistic studies, to alter pharmacokinetic profiles, and as internal standards ...