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Potentiometric method for resistance's measurement of pyrazinamide in mycobacterium tuberculosis
(IEEE , 2014)
An experimental research of the drug pyrazinamide is analyzed and tested with potentiometric method. By understanding the biomechatronic system, consisted of a mechanism of action of the drug Pyrazinamide in a biological ...
Potential tuberculostatic agent: Micelle-forming pyrazinamide prodrug
(Wiley-Blackwell, 2006-06-01)
Pyrazinamide was condensed with the poly(ethylene glycol)-poly(aspartic acid) copolymer (PEG-PASP), a micelle-forming derivative was obtained that was characterized in terms of its critical micelle concentration (CMC) and ...
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
(Wiley-Blackwell, 2007-11-01)
Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic ...
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
(Wiley-Blackwell, 2007-11-01)
Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic ...
Potential tuberculostatic agent: Micelle-forming pyrazinamide prodrug
(Wiley-Blackwell, 2006-06-01)
Pyrazinamide was condensed with the poly(ethylene glycol)-poly(aspartic acid) copolymer (PEG-PASP), a micelle-forming derivative was obtained that was characterized in terms of its critical micelle concentration (CMC) and ...
Evaluation of the microscopic observation drug susceptibility assay for detection of Mycobacterium tuberculosis resistance to pyrazinamide
(Wiley-Blackwell, 2011-12-01)
The microscopic observation drug susceptibility assay (MODS) was evaluated to determine susceptibility to pyrazinamide in Mycobacterium tuberculosis, and compared with the broth microdilution method (BMM), absolute ...
Evaluation of the microscopic observation drug susceptibility assay for detection of Mycobacterium tuberculosis resistance to pyrazinamide
(Wiley-Blackwell, 2011-12-01)
The microscopic observation drug susceptibility assay (MODS) was evaluated to determine susceptibility to pyrazinamide in Mycobacterium tuberculosis, and compared with the broth microdilution method (BMM), absolute ...
Pyrazinoic acid efflux rate in Mycobacterium tuberculosis is a better proxy of pyrazinamide resistance
(Elsevier, 2012)
Pyrazinamide is one of the most important drugs in the treatment of latent Mycobacterium tuberculosis infection. The emergence of strains resistant to pyrazinamide represents an important public health problem, as both ...
EFFECTS OF PYRAZINAMIDE ON PREGNANT ALBINO RATS
(Sociedad Chilena de Anatomía, 2003)
A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance
(BioMed Central, 2017)
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment ...