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CCP1/Nna1 functions in protein turnover in mouse brain: Implications for cell death in Purkinje cell degeneration mice
(FEDERATION AMER SOC EXP BIOL, 2010)
Purkinje cell degeneration (pcd) mice have a mutation within the gene encoding cytosolic carboxypeptidase 1 (CCP1/Nna1), which has homology to metallocarboxypeptidases. To assess the function of CCP1/Nna1, quantitative ...
A novel pathogenic mechanism for cerebellar lesions produced by Solanum bonariense in cattle
(American Association of Veterinary Laboratory Diagnosticians, 2015-05)
Intoxication with Solanum bonariense in cattle causes cerebellar cortical degeneration with perikaryal vacuolation, axonal swelling, and death primarily of Purkinje cells, with accumulation of electron-dense residual storage ...