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Orphan Formulations for Pediatric Use: Development and Stability Control of Two Sildenafil Citrate Solutions for the Treatment of Pulmonary Hypertension
(Springer, 2020-08)
Sildenafil citrate causes vasodilatation, relaxation of the smooth muscle, and reduction of pulmonary arterial pressure. The latter property makes sildenafil citrate efficient for the treatment of cardiovascular diseases, ...
Desenvolvimento de nanocápsulas poliméricas para liberação pulmonar do dipropionato de beclometasona
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2013-03-22)
Polymeric nanocapsules have been studied extensively for drug delivery by various routes of administration. Currently, the nanoencapsulation of drugs is considered the most efficient means of ensuring controlled release, ...
Fed and Fasting Bioequivalence Study for Two Formulations of Bosentan 125 Mg Tablets in Healthy Colombian People
(Journal of J Bioequivalence & Bioavailability, 2015)
This is a pharmacokinetic study of two formulations containing Bosentan 125 mg, in order to compare the
bioavailability between the Test product (Bosentan produced by Tecnoquímicas S.A. laboratory, Colombia) and
the Reference ...
An inhalable powder formulation based on micro-and nanoparticles containing 5-fluorouracil for the treatment of metastatic melanoma
(2018-02-01)
Melanoma is the most aggressive and lethal type of skin cancer, with a poor prognosis because of the potential for metastatic spread. The aim was to develop innovative powder formulations for the treatment of metastatic ...
Proposta de um protocolo de terapia celular para o tratamento da doença pulmonar obstrutiva crônica
(Elsevier B.V., 2014-03-01)
The main feature of pulmonary emphysema is airflow obstruction resulting from the destruction of the alveolar walls distal to the terminal bronchioles. Existing clinical approaches have improved and extended the quality ...
Formulation and characterization of polysaccharide microparticles for pulmonary delivery of sodium cromoglycate
(Springer, 2017-07)
Sodium cromoglycate (SC) is an antiasthmatic and antiallergenic drug commonly used for chronic inhalation therapy, however many daily intakes are required due to the fast drug clearance from airways. For these reasons, ...
Smart lipid nanoparticles containing levofloxacin and DNase for lung delivery. Design and characterization
(Elsevier Science, 2016-03)
Levofloxacin (LV) is a hydrophilic broad-spectrum antibiotic commonly used in pulmonary treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic fibrosis (CF) disease. In order to study ...