Buscar
Mostrando ítems 1-10 de 2097
Synergy of DNA-bending nucleoid proteins and macromolecular crowding in condensing DNA
(2007-10-01)
Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...
Synergy of DNA-bending nucleoid proteins and macromolecular crowding in condensing DNA
(2007-10-01)
Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...
Zinc fingers: DNA binding and protein-protein interactions
(Sociedad de Biología de Chile, 2000)
Experimental snapshots of a protein-DNA binding landscape
(National Academy of Sciences, 2010-04)
Protein recognition of DNA sites is a primary event for gene function. Its ultimate mechanistic understanding requires an integrated structural, dynamic, kinetic, and thermodynamic dissection that is currently limited ...
Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: The Pax6 example
(Oxford University Press, 2010-11)
Quite often a single or a combination of protein mutations is linked to specific diseases. However, distinguishing from sequence information which mutations have real effects in the protein's function is not trivial. Protein ...
Free energy contributions to direct readout of a DNA sequence
(American Society for Biochemistry and Molecular Biology, 2005-09)
The energetic contributions of individual DNA-contacting side chains to specific DNA recognition in the human papillomavirus 16 E2C-DNA complex is small (less than 1.0 kcal mol-1), independent of the physical and chemical ...
Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)