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The influence of non-protein thiols on DNA damage induced by bleomycin in single human cells
(Begell House, 2016-03)
Nonprotein thiols are considered radioprotectors, preventing DNA damage by ionizing radiation. Because bleomycin (BLM) is a radiomimetic agent, it was proposed that thiols may prevent DNA damage produced by this antibiotic. ...
Conferring specificity in redox pathways by enzymatic thiol/disulfide exchange reactions
(Taylor & Francis Ltd, 2016-02-01)
Thiol-disulfide exchange reactions are highly reversible, displaying nucleophilic substitutions mechanism (S(N)2 type). For aliphatic, low molecular thiols, these reactions are slow, but can attain million times faster ...
Effect of thiol compounds on bleomycin-induced DNA and chromosome damage in human cells
(Heldref Publications, 2013-02)
Non-protein thiols are considered radioprotectors, preventing DNA damage by ionizing radiation. As bleomycin (BLM) is a radiomimetic agent it was proposed that thiols may prevent DNA damage produced by this antibiotic. ...
HNO is produced by the reaction of NO with thiols
(Universidade Federal de Minas GeraisBrasilICX - DEPARTAMENTO DE QUÍMICAUFMG, 2017)
Thiol-disulfide proteins of stallion epididymal spermatozoa
(Elsevier, 2015)
Effects of isocoumarins isolated from Paepalanthus bromelioides on mitochondria: Uncoupling, and induction/inhibition of mitochondrial permeability transition
(Elsevier B.V., 2006-06-10)
Isolated mitochondria may undergo uncoupling, and in presence of Ca2+ at different conditions, a mitochondrial permeability transition (MPT) linked to protein,thiol oxidation, and demonstrated by CsA-sensitive mitochondrial ...
Effects of isocoumarins isolated from Paepalanthus bromelioides on mitochondria: Uncoupling, and induction/inhibition of mitochondrial permeability transition
(Elsevier B.V., 2006-06-10)
Isolated mitochondria may undergo uncoupling, and in presence of Ca2+ at different conditions, a mitochondrial permeability transition (MPT) linked to protein,thiol oxidation, and demonstrated by CsA-sensitive mitochondrial ...
Thiol oxidation by nitrosative stress: Cellular localization in human spermatozoa
(Informa Healthcare, 2016-09)
Peroxynitrite is a highly reactive nitrogen species and when it is generated at high levels it causes nitrosative stress, an important cause of impaired sperm function. High levels of peroxynitrite have been shown to ...
Effect of three non-protein thiols on CHO cells exposed to low doses of X-radiation
(Inderscience, 2013)
The goals of this study were to determine whether cysteamine, β-mercaptohetanol and glutathione protect CHO K1 cells against chromosomal aberrations induced by low doses of X-radiation, as well as whether radiation protection ...