Buscar
Mostrando ítems 1-10 de 43
Reproductive actions of prolactin mediated through short and long receptor isoforms
(Elsevier Ireland, 2014-01)
Prolactin (PRL) is a polypeptide hormone with a wide range of physiological functions, and is critical for female reproduction. PRL exerts its action by binding to membrane bound receptor isoforms broadly classified as the ...
Prolactin receptor antagonism in mouse anterior pituitary: effects on cell turnover and prolactin receptor expression
(American Physiological Society, 2012-01)
Since anterior pituitary expresses prolactin receptors, prolactin secreted by lactotropes could exert autocrine or paracrine actions on anterior pituitary cells. In fact, it has been observed that prolactin inhibits its ...
Effects of metoclopramide-induced hyperprolactinemia on the prolactin receptor of murine endometrium
(ELSEVIER SCIENCE INCNEW YORK, 2010)
Objective: To evaluate the effects of metoclopramide-induced hyperprolactinemia, on the prolactin receptor of murine endometrium. Design: Experimental study using the RNA extraction to detect tissue prolactin recepter ...
Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer
(Impact Journals, 2020-12)
Progesterone receptor (PR) isoforms can drive unique phenotypes in luminal breast cancer (BC). Here, we hypothesized that PR-B and PR-A isoforms differentially modify the cross-talk between prolactin and fatty acid synthase ...
Prolactin and Prolactin Receptor Expression In Cervical Intraepithelial Neoplasia and Cancer
(Pathology & Oncology Research, 2015)
Prolactin induces apoptosis of lactotropes in female rodents
(Public Library Of Science, 2014-05)
Anterior pituitary cell turnover occurring during female sexual cycle is a poorly understood process that involves complex regulation of cell proliferation and apoptosis by multiple hormones. In rats, the prolactin (PRL) ...
Estrogen receptors and signaling pathways in lactotropes and somatotropes
(Karger, 2010-12)
Estrogens are crucial determinants in the regulation of anterior pituitary function and maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both classical and non-classical mechanisms of ...
Increased expression of SNARE proteins and synaptotagmin IV in islets from pregnant rats and in vitro prolactin-treated neonatal islets
(Sociedad Biolgia ChileSantiagoChile, 2006)
Mycobacterium bovis infection in cattle induces differential expression of prolactin receptor isoforms in macrophages
(2013)
Prolactin receptor (PRLr) is a member of the cytokine receptor superfamily 1 showing tissue specific structural diversity. Expression of PRLr isoforms in lymphoid tissues has been associated with immunomodulatory function ...
Lactation deficit in OFA hr/hr rats may be caused by differential sensitivity to stress compared with Wistar and Sprague Dawley rats
(Taylor & Francis Ltd, 2012-07)
OFA hr/hr (OFA) rats present a major lactation deficit that impairs offspring survival. To explore whether abnormal stress responsiveness causes this deficit, we compared their hormonal (prolactin, progesterone, and ...