The cerebellum is an important organ to study development in the central nervous system. When matured, the cerebellum presents a well-defined three-layered cortex. Its development initiates during the embryonic period and ...

The role played by glial cells in the development of the central nervous system is not completely understood and the interaction of those cells with neurons is extremely important to the correct development of the brain. ...

Várias doenças humanas atualmente conhecidas têm causas genéticas. Uma maneira de se entender as alterações moleculares que levam a essas doenças é através da análise da disfunção de um gene, que pode ser feito usando ...

Methylglyoxal (MG) is a α-oxoaldehyde compound formed mainly as co-product from glycolysis. Due its high glicative capacity, it is considered the major precursor of advanced glycation end-products (AGEs). Although the ...

TThe cerebellum is a region of the central nervous system is responsible for motor coordination and balance. In the embryonic period, the most populous cerebellar neuron, the granular cells, proliferate by Sonic Hedgehog ...

CART (Cocaine- Amphetamine Regulated Transcript} fue descubierto como un RNAmque es inducido por una dosis aguda de cocaína y también de anfetamina en el estriado de cerebro de rata. A partir de su descubrimiento el ...