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Circulation of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains in Mexico
(2015-01-07)
Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB ...
Circulation of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains in Mexico
(2014-01-01)
Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB ...
Activity of semi-synthetic mulinanes against MDR, pre-XDR, and XDR strains of mycobacterium tuberculosis
(MDPI, 2021)
Tuberculosis causes more than 1.2 million deaths each year. Worldwide, it is the first cause of
death by a single infectious agent. The emergence of drug-resistant strains has limited pharmacological treatment of the ...
Distribuição da frequência de cepas de Mycobacterium tuberculosis multidroga resistentes (MDR) e extensivamente resistentes (XDR) do estado de São Paulo
(Universidade Federal de São Paulo (UNIFESP), 2020-05-06)
Tuberculosis is a disease susceptible to drug treatment, but the incorrect and irregular use of anti-tuberculosis drugs and prolonged treatment created selective conditions that promoted the emergence of resistance or ...
Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria
(Amer Chemical Soc, 2022-01-13)
A series of indolyl-3-methyleneamines incorporating lipophilic side chains were designed through a structural rigidification approach and synthesized for investigation as new chemical entities against Mycobacterium ...
Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria
(Amer Chemical Soc, 2021-12-08)
A series of indolyl-3-methyleneamines incorporating lipophilic side chains were designed through a structural rigidification approach and synthesized for investigation as new chemical entities against Mycobacterium ...
Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria
(2022-01-13)
A series of indolyl-3-methyleneamines incorporating lipophilic side chains were designed through a structural rigidification approach and synthesized for investigation as new chemical entities against Mycobacterium ...
Factores de riesgo para tuberculosis pulmonar pre extremadamente resistente en pacientes con tuberculosis pulmonar multidrogo resistente en el Hospital Regional Docente de Trujillo
(Universidad Nacional de TrujilloPE, 2022-07-01)
Introducción: La tuberculosis es la enfermedad infecciosa responsable de la mayoría de las muertes en todo el mundo. La compleja historia natural de Mycobacterium tuberculosis implica que las personas con infecciones ...
Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a multicentre cohort study
(Elsevier, 2021)
Background: Drug resistance threatens global tuberculosis control. We aimed to examine mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of results from drug ...