During the first steps of the gamete interaction, the proacrosin/acrosin system seems to play a crucial role in the secondary binding, holding acrosome-reacted spermatozoa during their passage through the zona pellucida. ...

Recombinant human zona pellucida protein C expressed in Chinese hamster ovary cells associates to the acrosomal region of human spermatozoa and inhibits sperm-zona pellucida interaction in the hemizona assay. Recombinant ...

Objective: To study the effect of the human tubal tissue conditioned medium (CM) on sperm parameters related to sperm-zona pellucida interaction. Design: Controlled experimental laboratory study. Setting: Research laboratory. ...

Zona pellucida (ZP) is an extracellular matrix surrounding the mammalian oocyte. In most mammalian species this matrix consists of three families of glycoproteins likely to suffer several postraductional modifications to ...

In a previous paper we demonstrated that boar β-acrosin recombinant proteins were able to bind non-enzymatically to solubilized pig zona pellucida (ZP) glycoproteins. Here we report the participation of boar β-acrosin in ...