Recombinant human zona pellucida protein C produced in Chinese hamster ovary cells binds to human spermatozoa and inhibits sperm-zona pellucida interaction

Marin Briggiler, Clara Isabel; Gonzalez Echeverría, María F.; Harris, Jeffrey D.; Vazquez, Monica Hebe

Artículos de revistas

Fecha

2008-09

Registro en:

Marin Briggiler, Clara Isabel; Gonzalez Echeverría, María F.; Harris, Jeffrey D.; Vazquez, Monica Hebe; Recombinant human zona pellucida protein C produced in Chinese hamster ovary cells binds to human spermatozoa and inhibits sperm-zona pellucida interaction; Elsevier Science Inc; Fertility and Sterility; 90; 3; 9-2008; 879-882

0015-0282

http://hdl.handle.net/11336/25532

1556-5653

CONICET Digital

CONICET

http://repositorioslatinoamericanos.uchile.cl/handle/2250/1894582

Autor

Marin Briggiler, Clara Isabel

Gonzalez Echeverría, María F.

Harris, Jeffrey D.

Vazquez, Monica Hebe

Institución

Consejo Nacional de Investigaciones Científicas y Tecnológicas (Argentina)

Resumen

Recombinant human zona pellucida protein C expressed in Chinese hamster ovary cells associates to the acrosomal region of human spermatozoa and inhibits sperm-zona pellucida interaction in the hemizona assay. Recombinant human zona pellucida protein C may be a useful tool toward the development of diagnostic methods for male factor infertility and the elucidation of the molecular basis of fertilization.

Materias

HUMAN SPERMATOZOA

BINDING TO ZP

RECOMBINANT ZP GLYCOPROTEINS

ACROSOMAL EXOCYTOSIS

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