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Drug-targeting in combined cancer chemotherapy: tumor growth inhibition in mice by association of paclitaxel and etoposide with a cholesterol-rich nanoemulsion
(SPRINGERDORDRECHT, 2012)
Lipid nanoemulsions (LDE) may be used as carriers of paclitaxel (PTX) and etoposide (ETP) to decrease toxicity and increase the therapeutic action of those drugs. The current study investigates the combined chemotherapy ...
PTX3 - Um novo marcador da inflamação das vias aéreas?
(Florianópolis, 2014)
Micelas poliméricas carreadoras de paclitaxel: potencial nanoplataforma teranóstica anticancer
(Universidade Federal de Minas GeraisBrasilFARMACIA - FACULDADE DE FARMACIAPrograma de Pós-Graduação em Ciências FarmacêuticasUFMG, 2019-10-04)
Polymeric micelles (PM) are nanostructured carriers used in the delivery of
hydrophobic drugs and/or imaging agents to solid tumors by passive targeting, enabling
an anti-cancer theranostic platform. From this, our ...
Pretreatment with pentoxifylline attenuates lung injury induced by intestinal ischemia/reperfusion in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2011-12-01)
PURPOSE: To investigate the protective effect of pentoxifylline against the lung injury observed after intestinal ischemia (I) followed by a period of reperfusion (R). METHODS: Twenty-eight male Wistar rats were equally ...
Avaliação do papel da pentraxina 3 na biologia de células tumorais humanas
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOLOGIA GERALPrograma de Pós-Graduação em GenéticaUFMG, 2018-02-26)
Melanoma is a type of cancer characterized by malignant transformation of melanocytes. Different types of molecular factors have been depicted as being important for melanoma progression, such as overexpression of ...
Caracterización molecular de Bordetella pertussis en Colombia, 1995-2014
(2017-12-28)
La tosferina una enfermedad causada por Bordetella pertussis, prevenible por vacuna que en los últimos años ha tenido un importante aumento de casos confirmados en Colombia con una incidencia de 8,5 X 100.000 habitantes ...
Avaliação das propriedades físico-químicas e estruturais de lipossomas pH-sensíveis recobertos com polietilenoglicol carreadores de paclitaxel
(Universidade Federal de Minas GeraisUFMG, 2015-02-26)
Paclitaxel (PTX) is a chemotherapeutic agent that has been shown significant antitumor activity for the treatment of a variety of cancers. However, the low solubility of PTX in aqueous medium represents a barrier to the ...
Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides
(Elsevier Science, 2015-06)
Molecular interactions between the anti-cancer agent Paclitaxel (Ptx), and two gangliosides with different sialic acid content, GM1 and GD1a, were investigated using the Langmuir film balance technique. Ptx showed interfacial ...
Self-assembled micelles of the (lipo) glycopeptides, teicoplanin, as taxane nanocarriers
(IOP Publishing, 2021-11)
The use of nanoparticles is one of the strategies currently studied to minimize the toxicity and lack of tissue specificity of many cancer drugs used in chemotherapy. In this research the physicochemical and biological ...