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The prostate response to prolactin modulation in adult castrated rats subjected to testosterone replacement
(2017-12-01)
Despite the androgenic dependence, other hormones, growth factors, and cytokines are necessary to support prostatic growth and maintain the glandular structure; among them, prolactin is a non-steroidal hormone secreted ...
Prolactin receptor antagonism in mouse anterior pituitary: effects on cell turnover and prolactin receptor expression
(American Physiological Society, 2012-01)
Since anterior pituitary expresses prolactin receptors, prolactin secreted by lactotropes could exert autocrine or paracrine actions on anterior pituitary cells. In fact, it has been observed that prolactin inhibits its ...
Prolactin: the bright and the dark side
(Oxford University Press, 2017-06)
Prolactin is a phylogenetically old signaling molecule whose gene can be traced to lampreys more than 500 million years ago. This fact poses the question of aprimitive function for prolactin, which would explain its retention ...
Opioid modulation of prolactin secretion induced by stress during late pregnancy: Role of ovarian steroids
(Elsevier, 2014-06)
Background: The opioid system modulates prolactin release during late pregnancy. Its role and the participation of ovarian hormones in this modulation are explored in ether stress-induced prolactin release. Methods/Results: ...
Reproductive actions of prolactin mediated through short and long receptor isoforms
(Elsevier Ireland, 2014-01)
Prolactin (PRL) is a polypeptide hormone with a wide range of physiological functions, and is critical for female reproduction. PRL exerts its action by binding to membrane bound receptor isoforms broadly classified as the ...
Smoking effects on prolactin at the end of pregnancy
(1995)
The blocking effect of nicotine on prolactin during lactation has been studied in animals and human beings, but limited research has been conducted in the last period of pregnancy in smoking mothers. In Chile, the majority ...
Use of Prolactin Receptor Antagonist to Better Understand Prolactin Regulation of Pituitary Homeostasis
(Karger, 2013-09)
he anterior pituitary is permanently regulated by processes of apoptosis and proliferation in order to maintain tissue homeostasis. Several factors have been implicated in this regulation and lately, prolactin (PRL) has ...
Zinc does not inhibit prolactin secretion during insulin-induced hypoglycemia in normal men
(2006-03-01)
Zinc (Zn ++) has been shown as an important physiological inhibitor of pituitary PRL release, and Zn ++ and PRL could be involved in a negative feedback regulatory loop. However, this inhibitory effect has not been detected ...