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Dengue Non-structural Protein 5 Polymerase Complexes With Promyelocytic Leukemia Protein (PML) Isoforms III and IV to Disrupt PML-Nuclear Bodies in Infected Cells
(Frontiers Media S.A., 2019-08)
Dengue virus (DENV) threatens almost 70% of the world's population, with no therapeutic currently available. The severe, potentially lethal forms of DENV disease (dengue hemorrhagic fever/dengue shock syndrome) are associated ...
Nuclear subcompartments: an overview
(Wiley-Blackwell, 2017)
The advance in biochemical and microscopy techniques has revealed the complexity and intricate nucleoplasm structure. Several subcompartments were identified in nucleus and the importance of these subcompartments in processes ...
MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs
(Nature Publishing Group, 2012-06)
MAGE-A genes are a subfamily of the melanoma antigen genes (MAGEs), whose expression is restricted to tumor cells of different origin and normal tissues of the human germline. Although the specific function of individual ...
Cellular Promyelocytic Leukemia Protein Is an Important Dengue Virus Restriction Factor
(Public Library Of Science, 2015-05)
The intrinsic antiviral defense is based on cellular restriction factors that are constitutively expressed and, thus, active even before a pathogen enters the cell. The promyelocytic leukemia (PML) nuclear bodies (NBs) are ...
Rol antiviral intrínseco de PML en la infección con flavivirusRole of PML in the intrinsic immunity against flaviviruses
(2018-01-01)
La inmunidad intrínseca es mediada por proteínas expresadas constitutivamente por la célula y que pueden bloquear directamente la replicación viral. Mientras que la activación de la respuesta inmune innata a través de la ...
Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase
(Royal Soc ChemistryCambridgeInglaterra, 2011)
Evidence for the interaction of the regulatory protein Ki-1/57 with p53 and its interacting proteins
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)
Evaluación de la calidad de agua del río Lupique de la comunidad Jimbitono, mediante la identificación de macro invertebrados bentónicos como bioindicadores
(Escuela Superior Politécnica de Chimborazo, 2022-06-07)
This study aimed to evaluate the water quality in the river Lupique, located in Jimbitono community, through the ICA-NSF index based on the physicochemical and microbiological parameters and also to identify the benthic ...