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Peptides and metallic nanoparticles for biomedical applications
(2007)
In this review, we describe the contribution of peptides to the biomedical applications of metallic nanoparticles. We also discuss strategies for the preparation of peptide-nanoparticle conjugates and the synthesis of the ...
Targeting tumors using peptides
(Multidisciplinary Digital Publishing Institute, 2020-02)
To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure ...
Recent trends in protein and peptide-based biomaterials for advanced drug delivery
Abstract: Engineering protein and peptide-based materials for drug delivery applications has
gained momentum due to their favorable biochemical and biophysical properties over synthetic
materials, including biocompatibility, ...
A conjugate of the lytic peptide Hecate and gallic acid: structure, activity against cervical cancer, and toxicity
(Springer, 2015-07-01)
Conjugate compounds constitute a new class of molecules of important biological interest mainly for the treatment of diseases such as cancer. The N-terminus region of cationic peptides has been described as important for ...
Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide
(2010)
Background & aims: Gold nanoparticles (GNPs) have promising applications for drug delivery as well as for the diagnosis and treatment of several pathologies, such as those related to the CNS. However, GNPs are retained in ...
Gold nanoparticles as an efficient drug delivery system for GLP-1 peptides
(Elsevier B.V., 2017)
© 2017 Elsevier B.V. In this work, the potential application of gold nanoparticles for GLP-1 analogues delivery was studied. For this purpose, the original sequence of the incretin GLP-1 was slightly modified in the ...
Gold nanoparticles as an efficient drug delivery system for GLP - 1 peptides
(Elsevier, 2017)
In this work, the potential application of gold nanoparticles for GLP-1 analogues delivery was studied. For this purpose, the original sequence of the incretin GLP-1 was slightly modified in the C-terminal region by adding ...
Antimicrobial activity of RP-1 peptide conjugate with ferrocene group
(2020-01-01)
Parasitic diseases are a neglected and serious problem, especially in underdeveloped countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent challenge due to its high incidence and severity. At ...
Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a tumor cell line
(2010)
Functionalization of gold nanoparticles (AuNPs) with both a targeting peptide (an analogue of the peptide Bombesin) and a drug peptide ligand (an analogue of the RAF peptide) with the aim of improving selectivity in the ...
Synthesis and In Vivo Evaluation of the Biodistribution of a F-18-Labeled Conjugate Gold-Nanoparticle-Peptide with Potential Biomedical Application
(AMER CHEMICAL SOC, 2012-03)
Gold nanoparticles (AuNPs) have been extensively used in biological applications because of their biocompatibility, size, and ease of characterization, as well as an extensive knowledge of their surface chemistry. These ...