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Solid-phase peptide synthesis in highly loaded conditions
(Academic Press Inc. Elsevier B.V., 2011-02-01)
The use of very highly substituted resins has been avoided for peptide synthesis due to the aggravation of chain-chain interactions within beads. To better evaluate this problem, a combined solvation-peptide synthesis ...
Solid-phase peptide synthesis in highly loaded conditions
(Academic Press Inc. Elsevier B.V., 2011-02-01)
The use of very highly substituted resins has been avoided for peptide synthesis due to the aggravation of chain-chain interactions within beads. To better evaluate this problem, a combined solvation-peptide synthesis ...
Comparative investigation of the cleavage step in the synthesis of model peptide resins: Implications for N-alpha-9-fluorenylmethyloxycarbonyl-solid phase peptide synthesis
(Pharmaceutical Soc Japan, 2007-03-01)
Based on our studies of the stability of model peptide-resin linkage in acid media, we previously proposed a rule for resin selection and a final cleavage protocol applicable to the N-alpha-tert-butyloxycarbonyl (Boc)-peptide ...
Synthesis of the peptide Ac-Wahx-KTTKS and evaluation of the ability to induce in vitro collagen synthesis
(2016-06-01)
In this work, we report the synthesis of a peptide analogue of the KTTKS, termed Ac-Wahx-KTTKS and evaluate its cytotoxicity and role in biosynthesis of collagen for future application in skin aging. The peptide was obtained ...
Synthesis of the Peptide Ac-Wahx-KTTKS and Evaluation of the Ability to Induce In Vitro Collagen Synthesis
(Bentham Science Publ Ltd, 2016-01-01)
In this work, we report the synthesis of a peptide analogue of the KTTKS, termed Ac-Wahx-KTTKS and evaluate its cytotoxicity and role in biosynthesis of collagen for future application in skin aging. The peptide was obtained ...
Peptide synthesis: chemical or enzymatic
(Pontificia Universidad Católica de Valparaíso, 2007)
The self-assembly of redox active peptides: Synthesis and electrochemical capacitive behavior
(2016-05-01)
The present work reports on the synthesis of a redox-tagged peptide with self-assembling capability aiming applications in electrochemically active capacitive surfaces (associated with the presence of the redox centers) ...
Combinatorial synthesis and directed evolution applied to the production of alpha-helix forming antimicrobial peptides analogues
(Bentham Science Publ Ltd, 2006-12-01)
Antimicrobial peptides (AMPs) are effector molecules of innate immune systems found in different groups of organisms, including microorganisms, plants, insects, amphibians and humans. These peptides exhibit several structural ...
On the role of surrounding regions in the fusion peptide in dengue virus infection
(2021-05-01)
Dengue virus infection depends on its fusion with the host membrane, where the binding occurs through interaction between proteins on the virus cell surface and specific viral receptors on target membranes. This process ...