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Design of affinity chromatography peptide ligands through combinatorial peptide libraries screening
(Springer, 2020)
In this chapter, a protocol to design affinity chromatography matrices with short peptide ligands immobilized for protein purification is described. The first step consists of the synthesis of a combinatorial peptide library ...
Desing, Synthesis and applications of short-peptide and peptidomimetic ligands for affinity chromatography
(Nova Science Publishers, 2018)
In the last few years many novel and alternative protein purificationprotocols have been designed using immobilized short-peptides orpeptidomimetics as ligands for affinity chromatography. These ligandsare easy to synthesize ...
Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library
(2001-11-06)
Despite vast efforts and expenditures in the past few decades, malaria continues to kill millions of persons every year, and new approaches for disease control are urgently needed. To complete its life cycle in the mosquito, ...
Targeting Plasmodium ligands on mosquito salivary glands and midgut with a phage display peptide library
(2001-11-06)
Despite vast efforts and expenditures in the past few decades, malaria continues to kill millions of persons every year, and new approaches for disease control are urgently needed. To complete its life cycle in the mosquito, ...
Netmhcpan-4.0: Improved peptide-MHC class I interaction predictions integrating eluted ligand and peptide binding affinity data
(American Association of Immunologists, 2017-11)
Cytotoxic T cells are of central importance in the immune system's response to disease. They recognize defective cells by binding to peptides presented on the cell surface by MHC class I molecules. Peptide binding to MHC ...
Improved peptide-MHC class II interaction prediction through integration of eluted ligand and peptide affinity data
(Springer, 2019-05)
Major histocompatibility complex (MHC) class II antigen presentation is a key component in eliciting a CD4+ T cell response. Precise prediction of peptide-MHC (pMHC) interactions has thus become a cornerstone in defining ...
Avian anticoccidial activity of a novel membrane-interactive peptide selected from phage display libraries
(Elsevier Science BvAmsterdamHolanda, 2002)
Targeting tumors using peptides
(Multidisciplinary Digital Publishing Institute, 2020-02)
To penetrate solid tumors, low molecular weight (Mw < 10 KDa) compounds have an edge over antibodies: their higher penetration because of their small size. Because of the dense stroma and high interstitial fluid pressure ...
Simple method to assess stability of immobilized peptide ligands against proteases
(John Wiley & Sons Ltd, 2017-09)
Although peptides are used as affinity chromatography ligands, they could be digested by proteases. Usually, peptide enzymatic stability is evaluated in solution, which differs from the resin-bounded peptide behavior. ...