The depression is one of the more commonly encountered psychiatric disorders of worldwide significance. However, the underlying pathophysiology has not been clearly defined. A possible etiologic role can be adjudged to the ...

Oxidative stress is an imbalance between pro-oxidants and antioxidants in favor of the pro-oxidants, leading to different responses depending on the level of pro-oxidants achieved and the duration of exposure. In this ...

The tumor angiogenesis process is believed to be dependent on an "angiogenic switch" formed by a cascade of biologic events as a consequence of the "cross-talk" between tumor cells and several components of local ...

Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal ...

The vascular manifestations associated with diabetes mellitus (DM) result from the dysfunction of several vascular physiology components mainly involving the endothelium, vascular smooth muscle and platelets. It is also ...

Oxygen is essential to the life of the aerobic organisms, and most is used for the intracellular generation of energy, where several molecules are formed by partial reduction of oxygen. Because of its short half-life, low ...