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Analysis of the opioid–opioid combinations according to the nociceptive stimulus in mice
(ELSEVIER, 2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and
morphine,whentwoofthemwere systemically combined in a 1:1 potency ratio, in the hot plate, the acetic
acid writhing, ...
Analysis of the opioid-opioid combinations according to the nociceptive stimulus in mice
(2010)
The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine, when two of them were systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid ...
Usos terapeuticos potenciales de los antagonistas opioides: Fisiopatologia y evidencia preclinica
Opioid system, which involved endogenous opioid peptides and their receptors (Miu, Kappa, delta and ORL), has a main role in the physiology of several systems. At the same time, there is cumulating evidence in the role of ...
Opioides, sexo e gênero
(Sociedade Brasileira para o Estudo da Dor, 2011)
JUSTIFICATIVA E OBJETIVOS: Sexo é um fator importante na modulação da experiência dolorosa. Evidências significativas têm demonstrado que a experiência à dor difere entre homens e mulheres, bem como na resposta à ativação ...
Antinociception induced by acute oral administration of sweet substance in young and adult rodents: The role of endogenous opioid peptides chemical mediators and mu(1)-opioid receptors
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
The present work aimed to investigate the effects of acute sucrose treatment on the perception of painful stimuli. Specifically, we sought to determine the involvement of the endogenous opioid peptide-mediated system as ...
mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat
(Blackwell Publishing LtdOxfordInglaterra, 2002)
Bases biológicas de la dependencia de las drogas : hacia un enfoque integral del problemaBiologic Bases of Drug Dependence : Towards an Integral Approach of the Problem
(Universidad de Antioquia, Facultad de MedicinaMedellín, Colombia, 2021)
O sistema opioide contribui para o efeito do tipo antidepressivo do disseleneto de m-trifluormetil-difenila em camundongos
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2018-07-20)
Depression is a mental disorder with complex pathophysiology and characterized by multiple symptoms, which makes it difficult to treat this disease. In the last decades, the opioid system has become the focus of depression ...
Racemic salsolinol and its enantiomers act as agonists of the µ-opioid receptor by activating the Gi protein-adenylate cyclase pathway
(Frontiers Media S.A., 2017)
© 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...