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Biotransformation of disperse dyes using nitroreductase immobilized on magnetic particles modified with tosyl group: Identification of products by LC-MS-MS and theoretical studies conducted with DNA
(2018-11-01)
The present work evaluates the action of nitroreductase enzyme immobilized on Tosylactivated magnetic particles (MP-Tosyl) on three disperse dyes which contain nitro and azo groups. The dyes included Disperse Red 73 (DR ...
Reduction of β-Glucuronidase and nitroreductase activity by yoghurt in a murine colon cancer model
(Sociedad Latinoamericana de Microscopía Electrónica; Centro Regional de Investigaciones Científicas y Tecnológicas, 2005-04)
Yoghurt feeding inhibits induced colon cancer in mice. Several studies showed the immunomodulatory effect of yoghurt which can explain this inhibition. It is possible that yoghurt bacteria can also affect gut flora enzymes ...
Development and analysis of furazolidone-resistant Escherichia coli mutants
(Wiley, 2015)
Furazolidone-resistant mutants were obtained from four clinical isolates of diarrhoeagenic Escherichia coli. The stability of the resistance and the frequency of mutation were established. The minimal inhibitory concentration ...
Trypanocidal Activity of Flavanone Derivatives
(MDPI, 2020)
Nifurtimox biotransformation to reactive metabolites or nitrite in liver subcellular fractions and model systems
(Elsevier Ireland, 2002-11)
Liver microsomal (mic); nuclei (N) and mitochondria (mit) anaerobically nitroreduce Nifurtimox (Nfx) in the presence of NADPH generating system. Simultaneous formation of small amounts of nitrite was observed in microsomes ...
Benznidazole-induced ultrastructural and biochemical alterations in rat colon
(Wiley Blackwell Publishing, Inc, 2000-11)
AIM: To study the effects of benznidazole (Bz), a drug used in the chemotherapy of the acute and the intermediate phase of Chagas' disease, on the colon of rats.
METHODS: Sprague Dawley male rats received Bz 100 mg/kg ig. ...