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Antifungal therapy: New advances in the understanding and treatment of mycosis
(2017-01-23)
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is ...
Searching new antifungals: The use of in vitro and in vivo methods for evaluation of natural compounds
(2016-04-01)
In the last decades, the increased number of immunocompromised patients has led to the emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of antifungals available and an increase in ...
New antimicrobial therapies used against fungi present in subgingival sites-A brief review
(Pergamon-Elsevier B.V. Ltd, 2011-10-01)
Although the main reservoir of Candida spp. is believed to be the buccal mucosa, these microorganisms can coaggregate with bacteria in subgingival biofilm and adhere to epithelial cells. The treatment of periodontal disease ...
New antimicrobial therapies used against fungi present in subgingival sites-A brief review
(Pergamon-Elsevier B.V. Ltd, 2011-10-01)
Although the main reservoir of Candida spp. is believed to be the buccal mucosa, these microorganisms can coaggregate with bacteria in subgingival biofilm and adhere to epithelial cells. The treatment of periodontal disease ...
New antimicrobial therapies used against fungi present in subgingival sites-A brief review
(Pergamon-Elsevier B.V. Ltd, 2014)
Antifungal activity of traditional medicinal plants from Argentina: effect of their combination with antifungal drugs
(Bentham Science Publishers, 2019-02)
The incidence of fungal infections has experienced a marked increase in the last two decades being limited to a few drugs with serious drawbacks. Combination therapy has emerged as an approach to improve the efficacy of ...
Conventional and alternative antifungal therapies to oral candidiasis
(Sociedade Brasileira de Microbiologia, 2010)
The multitude of targets for the immune system and drug therapy in the fungal cell wall
(Elsevier B.V., 2005-04-01)
Recent studies on fungi revealed that several cytosolic and membrane components migrate to the cell wall together with secreted proteins and biosynthetic polysaccharides to build a dynamic immunoreactive structure. New ...
Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents
(Hindawi Publishing Corporation, 2013-06)
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be ...