The multitude of targets for the immune system and drug therapy in the fungal cell wall

Nimrichter, Leonardo [UNIFESP]; Rodrigues, M. L.; Rodrigues, Elaine G. [UNIFESP]; Travassos, Luiz R. [UNIFESP]

Resenha

Fecha

2005-04-01

Registro en:

Microbes and Infection. Amsterdam: Elsevier B.V., v. 7, n. 4, p. 789-798, 2005.

1286-4579

http://repositorio.unifesp.br/handle/11600/28217

10.1016/j.micinf.2005.03.002

WOS:000229534600026

https://repositorioslatinoamericanos.uchile.cl/handle/2250/8615808

Autor

Nimrichter, Leonardo [UNIFESP]

Rodrigues, M. L.

Rodrigues, Elaine G. [UNIFESP]

Travassos, Luiz R. [UNIFESP]

Institución

Universidade Federal de São Paulo (Brasil)

Resumen

Recent studies on fungi revealed that several cytosolic and membrane components migrate to the cell wall together with secreted proteins and biosynthetic polysaccharides to build a dynamic immunoreactive structure. New aspects of fungal cell wall assembly and biosynthesis, focusing on the potential of glycolipids, melanin, heat-shock proteins, historic and surface antigens as targets of drugs and antifungal anti-bodies are discussed. (c) 2005 Elsevier SAS. All rights reserved.

Materias

antifungal therapy

antimicrobial antibodies

fungal cell walls

unfamiliar components

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