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Targeting autophagy in neurodegenerative diseases
(Elsevier Ltd, 2014)
© 2014 Elsevier B.V. All rights reserved. The most prevalent neurodegenerative disorders involve protein misfolding and the aggregation of specific proteins. Autophagy is becoming an attractive target to treat neurodegenerative ...
Potential applications of Desferrioxamine and other iron chelators for the clinical management of neurodegenerative diseases.
(Instituto de Física da Universidade de São Paulo.São Paulo, 2014-05-21)
Recently, potential applications of Desferrioxamine and other
iron chelators have attracted attention for the clinicai management of
neurodegenerative diseases. Several studies in the literature indicate that
metal ...
ER chaperones in neurodegenerative disease: Folding and beyond
(Elsevier, 2016)
Proteins along the secretory pathway are co-translationally translocated into the lumen of the endoplasmic reticulum (ER) as unfolded polypeptide chains. Afterwards, they are usually modified with N-linked glycans, correctly ...
Editorial: P2X7 Receptor Function in Neurodegenerative Diseases
(Frontiers Media, 2021)
Coenzyme Q(10) and its effects in the treatment of neurodegenerative diseases
(Universidade de São Paulo (USP), Conjunto Quimicas, 2009-10-01)
According to clinical and pre-clinical studies, oxidative stress and its consequences may be the cause or, at least, a contributing factor, to a large number of neurodegenerative diseases. These diseases include common and ...
Coenzyme Q(10) and its effects in the treatment of neurodegenerative diseases
(Universidade de São Paulo (USP), Conjunto Quimicas, 2009-10-01)
According to clinical and pre-clinical studies, oxidative stress and its consequences may be the cause or, at least, a contributing factor, to a large number of neurodegenerative diseases. These diseases include common and ...
Autophagy and its impact on neurodegenerative diseases: new roles for TDP-43 and C9orf72
(Frontiers, 2017-05-30)
Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), ...
Oxidative stress in neurodegenerative diseases: Mechanisms and therapeutic perspectives
(Hindawi Publishing Corporation, 2011)