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Brain development is impaired in c-fos -/- mice
(Impact Journals LLC, 2015-07)
c-Fos is a proto-oncogene involved in diverse cellular functions. Its deregulation has been associated to abnormal development and oncogenic progression. c-fos-/- mice are viable but present a reduction in their body weight ...
Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis
(2021)
Abstract
Background
The efficient regenerative abilities at larvae stages followed by a non-regenerative response after metamorphosis in froglets makes Xenopus an ideal ...
Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders : a novel perspective on congenital Zika syndrome
(2019-08)
Radial glial cells (RGCs) are the neural stem/progenitor cells (NSPCs) that give rise to most of neurons and glial cells that constitute the adult central nervous system. A hallmark of RGCs is their polarization along the ...
The Impact of Estrogen and Estrogen-Like Molecules in Neurogenesis and Neurodegeneration : Beneficial or Harmful?
(2021-03-08)
Estrogens and estrogen-like molecules can modify the biology of several cell types. Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of estrogen receptors, while the G protein-coupled ...
Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome
(Facultad de Medicina y Ciencia, 2019)
Radial glial cells (RGCs) are the neural stem/progenitor cells (NSPCs) that give rise to most of neurons and glial cells that constitute the adult central nervous system. A hallmark of RGCs is their polarization along the ...
Impacto biológico del proto-oncogen c-fos en células madres/progenitoras neurales
(2015)
c-Fos es una proteína codificada por un gen perteneciente a la familia de genes de expresión inmediata temprana. Junto a otras proteínas (Fra- 1, Fra-2, FosB y AF0sB), c-Fos es miembro de una familia de factores de ...
Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells
(Nature, 2021)
Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells
(NSPCs). Here we use high-resolution expression profiling to characterize the early ...