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Imaging single-channel calcium microdomains by total internal reflection microscopy
(Sociedad de Biología de Chile, 2004)
L-Type Calcium Channels Modulation by Estradiol
(Humana Press Inc., 2017)
High-Threshold Ca2+ channels behind gamma band activity in the pedunculopontine nucleus (PPN)
(American Physiological Society and The Physiological Society, 2015-07)
The pedunculopontine nucleus (PPN) is part of the Reticular Activating System, and active during waking and REM sleep. Previous results showed that all PPN cells plateau at gamma frequencies and intrinsic membrane oscillations ...
Differential effects of beta 1 and beta 2 subunits on BK channel activity
(ROCKEFELLER UNIV PRESS, 2005-04)
High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
Pore accessibility during C-type inactivation in Shaker K+ channels
(1998)
Shaker K+ channels inactivate through two distinct molecular mechanisms: N-type, which involves the N-terminal domain and C-type that appears to involve structural modifications at the external mouth of the channel. We ...
Food restriction promotes downregulation of myocardial L-type Ca2+ channels
(Canadian Science Publishing, Nrc Research Press, 2009-06-01)
Food restriction (FR) has been shown to impair myocardial performance. However, the mechanisms behind these changes in myocardial function due to FR remain unknown. Since myocardial L-type Ca2+ channels may contribute to ...
Food restriction promotes downregulation of myocardial L-type Ca2+ channels
(Canadian Science Publishing, Nrc Research Press, 2009-06-01)
Food restriction (FR) has been shown to impair myocardial performance. However, the mechanisms behind these changes in myocardial function due to FR remain unknown. Since myocardial L-type Ca2+ channels may contribute to ...
Intracellular mechanisms modulating gamma band activity in the pedunculopontine nucleus (PPN)
(Wiley Blackwell Publishing, Inc, 2016-06)
The pedunculopontine nucleus is a part of the reticular activating system, and is active during waking and REM sleep. Previous results showed that all PPN cells tested fired maximally at gamma frequencies when depolarized. ...
Pedunculopontine arousal system physiology – implications for insomnia
(Elsevier Science, 2015-04)
We consider insomnia a disorder of waking rather than a disorder of sleep. This review examines the role of the reticular activating system, especially the pedunculopontine nucleus, in the symptoms of insomnia, mainly ...
Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998-12-04)
We investigated the role of individual charged residues of the S4 region of a MaxiK channel (hSlo) in channel gating, We measured macroscopic currents induced by wild type (WT) and point mutants of hSlo in inside-out ...