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Cardiac cachexia and muscle wasting: definition, physiopathology, and clinical consequences
(2014)
Cachexia and muscle wasting are frequently observed in heart failure patients. Cachexia is a predictor of reduced survival, independent of important parameters such as age, heart failure functional class, and functional ...
Efects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicentre randomised trial
(2022)
Background: Chronic obstructive pulmonary disease (COPD) is the third cause of death worldwide. COPD is char‑acterised by dyspnoea, limited exercise tolerance, and muscle dysfunction. Muscle dysfunction has been linked to ...
Bile acids induce alterations in mitochondrial function in skeletal muscle fibers
(MDPI, 2022)
Cholestatic chronic liver disease is characterized by developing sarcopenia and elevated serum levels of bile acids. Sarcopenia is a skeletal muscle disorder with the hallmarks of muscle weakness, muscle mass loss, and ...
Role of oxidative stress as key regulator of muscle wasting during cachexia
(Hindawi Limited, 2018)
Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of muscular mass and the contractile capacity of the skeletal muscle as a consequence of muscular weakness and decreased force generation. ...
SARS-CoV-2/Renin–angiotensin system: Deciphering the clues for a couple with potentially harmful effects on skeletal muscle
(MDPI, 2020)
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) has produced significant health emergencies worldwide, resulting in the declaration by the World Health Organization of the coronavirus disease 2019 (COVID-19) ...
Lower values of handgrip strength and adductor pollicis muscle thickness are associated with hepatic encephalopathy manifestations in cirrhotic patients
(2016-08-01)
Hepatic encephalopathy (HE) is a late complication of liver cirrhosis and is clearly associated with poor outcomes. Chronic liver insufficiency leads to progressive muscle wasting, impairing ammonia metabolism and thus ...
Effects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicentre randomised trial
(BioMed Central Ltd, 2022-07)
Background: Chronic obstructive pulmonary disease (COPD) is the third cause of death worldwide. COPD is characterised by dyspnoea, limited exercise tolerance, and muscle dysfunction. Muscle dysfunction has been linked to ...
Cardiac cachexia: Perspectives for prevention and treatment
(2017-01-01)
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its occurrence predicts increased morbidity and mortality independent of important clinical variables such as age, ventricular function, ...