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Structure of the lectin mannose 6-phosphate receptor homology (MRH) domain of glucosidase II an enzyme that regulates glycoprotein folding quality control in the endoplasmic reticulum
(American Society for Biochemistry and Molecular Biology, 2013-06)
Here we report for the first time the three-dimensional structure of a mannose 6-phosphate receptor homology (MRH) domain present in a protein with enzymatic activity, glucosidase II (GII). GII is involved in glycoprotein ...
Structure of the Lectin MRH Domain of Glucosidase II, an Enzyme that Regulates Glycoprotein Folding Quality Control in the Endoplasmic Reticulum
(American Society For Biochemistry And Molecular Biology, 2013-04-05)
Here we report for the first time the three-dimensional structure of a mannose 6-phosphate receptor homology (MRH) domain present in a protein with enzymatic activity, glucosidase II (GII). GII is involved in glycoprotein ...
The receptor-like pseudokinase MRH1 interacts with the voltage-gated potassium channel AKT2
(2017)
The potassium channel AKT2 plays important roles in phloem loading and unloading. It can operate as inward-rectifying channel that allows H+-ATPase-energized K+ uptake. Moreover, through reversible post-translational ...
Glucosidase II and MRH-Domain Containing Proteins in the Secretory Pathway
(Bentham Science Publishers, 2015-01)
N-glycosylation in the endoplasmic reticulum (ER) consists of the transfer of a preassembled glycan conserved among species (Glc3Man9GlcNAc2) from a lipid donor to a consensus sequence within a nascent protein that is ...
Crystal Structure and Functional Analyses of the Lectin Domain of Glucosidase II: Insights into Oligomannose Recognition
(American Chemical Society, 2015-07)
N-Glycans are modified as part of a quality control mechanism during glycoprotein folding in the endoplasmic reticulum (ER). Glucosidase II (GII) plays a critical role by generating monoglucosylated glycans that are ...
Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo
(American Society for Cell Biology, 2011-06)
Glucosidase II (GII) sequentially removes the two innermost glucose residues from the glycan (Glc3Man9GlcNAc2) transferred to proteins. GII also participates in cycles involving the lectin/chaperones calnexin (CNX) and ...
Caracterización de los trastornos de la función sexual femenina en pacientes con esclerosis múltiple en el HUN en el año 2020
(Universidad Nacional de ColombiaBogotá - Medicina - Especialidad en Neurología ClínicaDepartamento de Medicina InternaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021)
La disfunción sexual puede afectar hasta el 70% de las pacientes con esclerosis múltiple (EM) según estudios previos y es un determinante importante de calidad de vida. En Colombia desconocemos los datos sobre los trastornos ...
Estudio de factibilidad para la producci?n y comercializaci?n mantequilla clarificada en la ciudad de Ibagu?
(Universidad de Ibagu?Ingenier?aIbagu?Ingenier?a Industrial, 2023)