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γ-Tubulin small complex formation is essential for early zebrafish embryogenesis
(Elsevier Ireland Ltd, 2018)
© 2018 The centrosomal protein γ-tubulin is part of the cytoplasmic γ-tubulin small (γ-TuSCs) and large complexes (γ-TuRCs). Both, molecular and cellular evidence indicate that γ-tubulin plays a central role in microtubule ...
Microtubules regulate brush border formation
(Wiley-liss, Div John Wiley & Sons Inc, 2018-02)
Most epithelial cells contain apical membrane structures associated to bundles of actin filaments, which constitute the brush border. Whereas microtubule participation in the maintenance of the brush border identity has ...
The complex dynamic network of microtubule and microfilament cytasters of the leech zygote
(Academic Press Inc., 2000)
The organization of the cytoskeleton in the early first interphase zygote and its involvement in organelle redistribution were studied in the glossiphoniid leech Theromyzon trizonare by confocal and electron microscopy, ...
The compound 14-keto-stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells
(1998)
We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium
flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...
A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
(Nature Publishing Group, 2018-12)
Emerging evidence indicates that microtubule-associated proteins (MAPs) are implicated in synaptic function; in particular, mice deficient for MAP6 exhibit striking deficits in plasticity and cognition. How MAP6 connects ...
Centrosomal AKAP350 and CIP4 act in concert to define the polarized localization of the centrosome and Golgi in migratory cells
(Company of Biologists, 2015-09-01)
The acquisition of a migratory phenotype is central in processes as diverse as embryo differentiation and tumor metastasis. An early event in this phenomenon is the generation of a nucleus-centrosome-Golgi back-to-front ...
Human Nek7-interactor Rgs2 Is Required For Mitotic Spindle Organization
(Landes Bioscience, 2015)