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How drugs modulate the performance of the human heart
(2022)
Many drugs interact with ion channels in the cells of our heart and trigger heart rhythm disorders with potentially fatal consequences. Computational modeling can provide mechanistic insight into the onset and propagation ...
Muscarinic stimulation and pinacidil produce similar facilitation of tachyarrhythmia induction in rat isolated atria
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2013)
Mecanismos Celulares E Moleculares Da Ação Antiarritímica Da Ranolazina Na Síndrome Do Qt Longo Do Tipo 3
(Universidade Federal de São Paulo (UNIFESP), 2018-10-25)
The Contractile Function Of The Heart Depends On The Proper Generation And Propagation Of The Electrical Signal By The Organ. Alterations In This Process Contribute To The Formation Of Cardiac Arrhythmias, Taking As An ...
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-19
The novel 2019 coronavirus disease (COVID-19), resulting from severe acute respiratory syndrome coronarvirus2 (SARS-CoV-2) infection, typically leads to respiratory failure in severe cases; however, cardiovascular injury ...
Regulation of the Cardiac Sodium/Bicarbonate cotransporter by Angiotensin II: potential contribution to structural, ionic and electrophysiological Myocardial remodelling
(Bentham Science Publishers, 2013-02)
The sodium/ bicarbonate cotransporter (NBC) is, with the Na+ /H+ exchanger (NHE), an important alkalinizing mechanism that maintains cellular intracellular pH (pHi). In the heart exists at least three isoforms of NBC, one ...
Modelagem de extrassístole associada a transiente de cálcio estocástico
(Universidade Federal de Juiz de Fora (UFJF)BrasilFaculdade de EngenhariaPrograma de Pós-graduação em Modelagem ComputacionalUFJF, 2022)