A mixed integer linear programming (MILP) for the detailed production planning of multiproduct batch plants is presented in this work. New timing decisions are incorporated to the model taking into account that an operation ...

This contribution introduces an efficient constraint programming (CP) model that copes with large-scale scheduling problems in multiproduct multistage batch plants. It addresses several features found in industrial ...

This work presents a multiperiod optimization model for multiproduct batch plants operating during several time periods with different characteristics because of seasonal and market fluctuations. This model simultaneously ...

Significant benefits can be obtained if the interactions among different decision levels are appropriately addressed and simultaneously solved. In this work, a MILP formulation for the supply chain design is presented which ...

This contribution presents a new Constraint Programming (CP) formulation to address the optimal operation of multiproduct continuous processes. In particular, facilities having continuous stages, which manufacture intermediate ...

In this paper, a heuristic method is presented for the simultaneous solution of the synthesis and design problems of batch plants. A detailed nonlinear program (NLP) model is developed that considers a superstructure to ...

The study of multiproduct assembly lines producing several models in a series of runs or campaigns is of special interest to modern industries. Assuming that the assembly line makes synchronous movements between workstations, ...

In this work we propose a model that simultaneously optimizes the process variables and the structure of a multiproduct batch plant for the production of recombinant proteins. The complete model includes process performance ...