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Development of novel microstructured lipid carriers for dissolution rate enhancement of albendazole
(2020-11-07)
Objective: This study aimed to develop a microstructured lipid carrier that improves the rate of dissolution of the active pharmaceutical ingredient
(API) Albendazole.
Methods: A solvent diffusion method was used for the ...
Nanotechnology-based lipid systems applied to resistant bacterial control: A review of their use in the past two decades
(2021-06-15)
The rate of infections caused by resistant bacteria to the antimicrobials available for human use grows exponentially every year, which generates major impacts on human health and the world economy. In the last two decades, ...
Lipid nanoparticles for the topical delivery of retinoids and derivatives
(Future Medicine Ltd., 2015)
Retinoids are lipophilic compounds that are highly used in cosmetics/therapeutics for skin disorders. Conventional formulations are limited by poor water solubility, high chemical/photochemical instability and the irritation ...
Exploiting solid lipid nanoparticles and nanostructured lipid carriers for drug delivery against cutaneous fungal infections
(Taylor & Francis Ltd, 2020-11-03)
Several types of cutaneous fungal infections can affect the population worldwide, such as dermatophytosis, cutaneous candidiasis, onychomycosis, and sporotrichosis. However, oral treatments have pronounced adverse effects, ...
Validation of an HPLC method for the determination of dibucaine encapsulated in solid lipid nanoparticles and nanostructured lipid carriers
(2013-11-27)
Dibucaine (DBC), used mainly in topical formulations, is one of the most potent long-acting local anesthetics, but is also one of the more toxic. Recently, solid lipid nanoparticles and nanostructured lipid carriers have ...
Validation of an HPLC Method for the Determination of Dibucaine Encapsulated in Solid Lipid Nanoparticles and Nanostructured Lipid Carriers
(Colegio Farmaceuticos Provincia de Buenos Aires, 2013-01-01)
Dibucaine (DBC), used mainly in topical formulations, is one of the most potent long-acting local anesthetics, but is also one of the more toxic. Recently, solid lipid nanoparticles and nanostructured lipid carriers have ...
Validation of an innovative analytical method for simultaneous quantification of curcumin and fluconazole using high-performance liquid chromatography from nanostructured lipid carriers
(2021-01-01)
Vulvovaginal candidiasis is a public health problem with a high incidence among female patients. Currently, there is an increase in the identification of Candida spp. resistant to current therapy, making it necessary to ...
Nano- and micro-particles as drug carriers
(Elsevier Ltd., 2020)
Advanced micro and nano-material therapeutic systems exhibit several advantages over conventional therapeutic systems. Great progresses in the development of improved drug delivery systems (DDS), including ...
Formulating SLN and NLC as innovative drug delivery systems for non-invasive routes of drug administration
(2020-01-01)
Colloidal carriers diverge depending on their composition, ability to incorporate drugs and applicability, but the common feature is the small average particle size. Among the carriers with the potential nanostructured ...
Comparative Study of Glyceryl Behenate or Polyoxyethylene 40 Stearate-Based Lipid Carriers for Trans-Resveratrol Delivery: Development, Characterization and Evaluation of the In Vitro Tyrosinase Inhibition
(2018-04-01)
Trans-resveratrol (RSV) is a natural compound with several properties, such as the ability to inhibit the tyrosinase enzyme, with potential application as a skin-lightning agent and for the treatment of skin disorders ...