Buscar
Mostrando ítems 1-10 de 543
A new experimental protocol for preferential differentiation of mouse embryonic stem cells into insulin-producing cells
(Cognizant Communication Corp, 2008-12)
Mouse embiyonic stem (ES) cells have the potential to differentiate into insulin-producing cells, but efficient protocols for in vitro differentiation have not been established. Here we have developed a new optimized ...
An efficient experimental strategy for mouse embryonic stem cell differentiation and separation of a cytokeratin-19-positive population of insulin-producing cells
(Wiley Blackwell Publishing, Inc, 2008-07-08)
Embryonic stem cells are a potential source for insulin‐producing cells, but existing differentiation protocols are of limited efficiency. Here, the aim has been to develop a new one, which drives development of embryonic ...
Characterization of the regenerated Insulin-producing cells following pancreatic β-cell destruction in zebrafish
(2021)
Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other
pancreatic cells raises the questions of the efficiency of the process and of the
functionality of the new Insulin-expressing cells. ...
Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets
(SpringerNew YorkEUA, 2010)
Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression
(Elsevier B.V., 2009-11-15)
Pancreatic cells are very sensitive to reactive oxygen species (ROS) and this might play an important role in beta cell death in diabetes. Dexamethasone is a synthetic diabetogenic glucocorticoid, which impairs pancreatic ...
Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression
(Elsevier B.V., 2009-11-15)
Pancreatic cells are very sensitive to reactive oxygen species (ROS) and this might play an important role in beta cell death in diabetes. Dexamethasone is a synthetic diabetogenic glucocorticoid, which impairs pancreatic ...
Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
(BMC, 2020)
Background: In type I diabetes mellitus (T1DM) pancreatic beta cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet ...
Microencapsulation of cellular aggregates composed of diferentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
(2020)
Background: In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transplant ...
Limited Capacity of Human Adult Islets Expanded In Vitro to Redifferentiate Into Insulin-Producing β-cells
(American Diabetes Association, 2007-03)
Limited organ availability is an obstacle to the widespread use of islet transplantation in type 1 diabetic patients. To address this problem, many studies have explored methods for expanding functional human islets in ...