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Impact of hypoxia on IGF-I, IGF-II, IGFBP-3, ALS and IGFBP-1 regulation and on IGF1R gene expression in children
(CHURCHILL LIVINGSTONEEDINBURGH, 2012)
Hypoxia is one of many factors involved in the regulation of the IGF system. However, no information is available regarding the regulation of the IGF system by acute hypoxia in humans. Objective: The aim of this study was ...
Association between IGF-I, IGF-IR and GHRH gene polymorphisms and growth and carcass traits in beef cattle
(Elsevier B.V., 2005-07-01)
Molecular biology techniques are of help in genetic improvement since they permit the identification, mapping and analysis of polymorphisms of genes encoding proteins that act on metabolic pathways involved in economically ...
Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis
(BIOSCIENTIFICA LTDBRISTOL, 2016)
Fsh Stimulates Spermatogonial Proliferation and Differentiation in Zebrafish via Igf3
(Endocrine Soc, 2015-10-01)
Growth factors modulate germ line stem cell self-renewal and differentiation behavior. We investigate the effects of Igf3, a fish-specific member of the igf family. Fsh increased in a steroid-independent manner the number ...
Genetic disorders of GH action pathway
(Churchill Livingstone, 2018-02)
While insensitivity to GH (GHI) is characterized by low IGF-I levels, normal or elevated GH levels, and lack of IGF-I response to GH treatment, IGF-I resistance is characterized by elevated IGF-I levels with normal/high ...
IGF-I Gene Therapy in Aging Rats Modulates Hippocampal Genes Relevant to Memory Function
(Gerontological Soc Amer, 2017-06)
In rats, learning and memory performance decline during normal aging, which makes this rodent species a suitable model to evaluate therapeutic strategies. In aging rats, insulin-like growth factor-I (IGF-I), is known to ...