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Sildenafil selectively inhibits acute pulmonary embolism-induced pulmonary hypertension
(Academic Press Ltd Elsevier Science LtdLondonInglaterra, 2005)
Presence of phosphodiesterase type 5 in the spinal cord and its involvement in bladder outflow obstruction related bladder overactivity
(Elsevier B.V., 2013-10-01)
Purpose: Phosphodiesterase type 5 inhibitors were recently introduced as a new treatment option for men with lower urinary tract symptoms. Safety and clinical effectiveness are well documented but the mode of action is ...
Sildenafil reverses hypoxic pulmonary hypertension in highland and lowland newborn sheep
(INT PEDIATRIC RESEARCH FOUNDATION, INC, 2008)
Perinatal exposure to chronic hypoxia induces sustained hypertension and structural and functional changes in the pulmonary vascular bed. We hypothesized that highland newborn lambs (HLNB, 3600 m) have a higher pulmonary ...
Sildenafil improves the beneficial haemodynamic effects of intravenous nitrite infusion during acute pulmonary embolism
(WILEY-BLACKWELL, 2008)
Acute pulmonary embolism produces acute pulmonary hypertension, which can be counteracted by activating the nitric oxide-cyclic guanosine 3`,5`-monophosphate (cGMP) pathway. While previous studies have shown that sildenafil ...
Effects of different inspired oxygen fractions on sildenafil-induced pulmonary anti-hypertensive effects in a sheep model of acute pulmonary embolism
(Elsevier B.V., 2015-04-15)
Aims: Sildenafil is a pulmonary anti-hypertensive agent whose action could be modified by different fractions of inspired oxygen (FiO(2)). We compared the effects of pure oxygen (FiO(2) > 90%) or room air (21% FiO(2)) ...
Effect of acute administration of sildenafil to rats with detrusor overactivity induced by chronic deficiency of nitric oxide
(Sociedade Brasileira de Urologia, 2013)
Efeito de diferentes frações inspiradas de oxigênio sobre a ação anti-hipertensiva pulmonar do sildenafil
(Universidade Estadual Paulista (Unesp), 2015-02-09)
Sildenafil is a pulmonary anti-hypertensive agent whose action could be modified by different fractions of inspired oxygen (FiO2). The effects of pure oxygen (FiO2 > 90%) or room air (21% FiO2) on the cardiopulmonary actions ...
Sildenafil for pulmonary hypertension treatment after cardiac surgery
(2005-03-01)
Objective: To report on the use of sildenafil for pulmonary hypertension treatment of a newborn patient after cardiac surgery. Description: A female, full term newborn infant with diagnosis of double outlet right ventricle, ...
Sildenafil for pulmonary hypertension treatment after cardiac surgery
(2005-03-01)
Objective: To report on the use of sildenafil for pulmonary hypertension treatment of a newborn patient after cardiac surgery. Description: A female, full term newborn infant with diagnosis of double outlet right ventricle, ...