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Presence of structural homologs of ubiquitin in haloalkaliphilic Archaea
(Springer, 2009-09)
Ubiquitin, a protein widely conserved in eukaryotes, is involved in many cellular processes, including proteolysis. While sequences encoding ubiquitin-like proteins have not been identified in prokaryotic genomes sequenced ...
Análise da hidrofobicidade na evolução de proteínas
(Universidade Estadual Paulista (UNESP), 2014)
The β-isoform of heat shock protein hsp-90 is structurally related with human microtubule-interacting protein Mip-90
(1999)
Through major research advances in the study of cytoskeletal organization, an integrated view of the complexity of this system has emerged. Recent findings on the microtubule-interacting protein Mip-90, which associates ...
Protein topology determines substrate-binding mechanism in homologous enzymes
(2018)
During evolution, some homologs proteins appear with different connectivity between secondary structures (different topology) but conserving the tridimensional arrangement of them (same architecture). These events can ...
Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs
(Medicina Oral S.L., 2018)
Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs
(SAGE PUBLICATIONS LTD, 2019)
In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ...
Intermolecular interactions of the malate synthase of Paracoccidioides spp
(2013-05-16)
Background: The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase (PbMLS) is important in the ...
Intermolecular interactions of the malate synthase of Paracoccidioides spp
(2013-05-16)
Background: The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase (PbMLS) is important in the ...